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Endocrine malignancies: a five-year retrospective analysis in a tertiary hospital

Author

Publication Information

Publication Type
Journal
Title
Philippine Journal of Internal Medicine
Frequency
Quarterly
Publication Date
July-September 2014
Volume
52
Issue
3
Page(s)
101-108

Abstract

Background: Endocrine malignancy in the Filipino


population has not been well documented particularly


on the incidence, prevalence, demographic profile


and survival rate. It is the aim of this study to


determine the prevalence rate and demographic


profile of all endocrine malignancies diagnosed at


a tertiary hospital.


Materials and Methods: This is a retrospective study


from March 2003 to March 2008. Data were obtained


from the Tumour Registry of St. Luke's Medical Center


Cancer Institute (SLMC-CI) and from the Annual


Report of the Diabetes, Thyroid and Endocrinology


Center (DTEC) Section of SLMC-Quezon City. Only


individuals with retrievable histopathology at this


institution were included in the study.


Statistical Analysis: Data were calculated using


percentages and proportions.


Results: There were a total of 855 cases of endocrine


malignancies documented in five years of which, 833


were cases of thyroid malignancies (97.4%). Fourteen


cases of adrenal cancer (1.60%), seven cases of


neuroendocrine carcinoma (0.79%), and one case of


parathyroid carcinoma (0.14%). There was no note


of pituitary cancer.


There were a total of 833 newly diagnosed


thyroid cancer: 652 papillary carcinoma (78.2%), 157


follicular carcinoma (18.8%), 11 anaplastic carcinoma


(1.32%); nine medullary thyroid cancer (1.08%); two


thyroid lymphoma (0.28%), one poorly differentiated


carcinoma (0.14%) and one metastatic to the thyroid


(0.14%).


Among the 14 adrenal cancers, seven cases


were due to adrenal cortical carcinoma, one


case was due to adrenal neuroblastoma and six


cases were due to adrenal metastases. Among the


neuroendocrine carcinomas, four were pancreatic


neuroendocrine carcinoma which included two


malignant insulinoma and three patients were extra


pancreatic neuroendocrine carcinoma.

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